In January 2015, Almiron signed for Newcastle United from Colombian club Atletico Nacional. The move was a significant one as it marked his first professional move to a Premier League side.

The Uruguayan forward made his debut for Newcastle on February 14, 2015, and he did not disappoint. In just his first match for the Magpies, he scored a hat-trick against Watford. This performance set the tone for what would be a prolific season for Almiron.

Throughout the season, Almiron continued to impress with his goal-scoring abilities. He scored a total of 19 goals in all competitions, including 7 in the Premier League alone. His performances earned him praise from fans and critics alike, and he became a key player for Newcastle throughout the season.

Almiron's success at Newcastle continued into the following season as well. He scored 8 goals in the Premier League in 2016-17, helping Newcastle finish in eighth place and qualify for Europa League football.

Overall, Almiron's time at Newcastle was a success story. He arrived with little fanfare but left with a reputation as one of the most dangerous forwards in the Premier League. His performances helped Newcastle secure their spot in Europe and cemented his status as a top-class talent in world football.